THEORETICAL ANALYSIS OF POLYCOMB-TRITHORAX SYSTEMS PREDICTS THAT POISED CHROMATIN IS BISTABLE AND NOT BIVALENT

Theoretical analysis of Polycomb-Trithorax systems predicts that poised chromatin is bistable and not bivalent

Polycomb and Trithorax group proteins regulate silent and active gene expression states, but chorulon hcg also allow poised states in pluripotent cells.Here the authors present a mathematical model that integrates data on Polycomb/ Trithorax biochemistry into a single coherent framework which predicts that poised chromatin is not bivalent here as p

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Participatory Scenario Development to Address Potential Impacts of Land Use Change: An Example from the Italian Alps

Changes to land use such as the removal of natural vegetation and expansion of urban areas can result in degradation of the landscape and an increase in hydro-meteorological risk.This has led to higher interest by decision-makers and scientists in the future consequences of these drivers.Scenario development can be a useful tool for addressing the

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A Comprehensive Primer on Transgender Health in India

Background: Transgender health care deals with the prevention, diagnosis, and treatment of physical and mental health conditions along with sex reassignment surgeries and hormonal therapies pertaining to transgender population.Despite the numerous positive developments and efforts made for the welfare of transgender individuals, the plight of these

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Social Innovation in Education and Social Service Organizations. Challenges, Actors, and Approaches to Foster Social Innovation

Social innovation became a widely discussed topic in politics, research funding programs, and business development.Recent European and US economic and science policies have set aside significant funds to generate and foster social innovation.In view of current challenges such as digitization, Work 4.0, inclusion or migrant integration, the question

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